Portrait of a woman with shoulder-length wavy brown hair, wearing a dark blue top, against a softly blurred indoor background.

Lisa Goodrich, Ph.D.

Professor of Neurobiology, Harvard Medical School
Vice Chair of Neurobiology, Harvard Medical School

Lisa Goodrich, PhD – People Feature

Professor of Neurobiology and Department Vice Chair in the Department of Neurobiology at Harvard Medical School.

If you prefer, you can view the visual layout directly on Canva by Neuro Coordinator.

Contact

Email: lisa_goodrich@hms.harvard.edu

Goodrich Lab website: goodrich.med.harvard.edu

The Goal

The Goodrich Lab studies how hearing circuits form and function, and what leads to their deterioration.

The Impact

Studying how the brain and ear work together to produce our sense of hearing offers insight into a key sensory system that people and animals use to navigate the world.

Hearing can be impaired by genetic mutations, infection, or exposure to excessively loud sounds. Deciphering the cellular and molecular mechanisms underlying the formation and function of auditory circuits may lead to improved protection of hearing and treatments for hearing loss.

This work has the potential to help people of all ages more fully enjoy the sounds that enrich our lives.

A Closer Look

Harvard Medicine Magazine — Spring 2020: 5 Questions with a Neurobiologist: A Conversation with Lisa Goodrich

Lisa reflects on the rewards and challenges of life as a researcher and offers advice for others interested in pursuing scientific research. She discusses the molecular origins of sensory circuits, the rewards of scientific discovery, and the importance of flexibility in research and career paths.

Harvard Medical School News — November 2011: Bioengineering for Hearing, Sight and Mobility

Dr. Goodrich presented her research at the inaugural Bertarelli Neuroengineering Symposium in Lausanne, Switzerland. Support from the Bertarelli Foundation funded a project in her lab with the potential to help people whose lives are affected by hearing loss.

The featured research focuses on understanding auditory hair cells and developing approaches that could support improved treatments for hearing loss.

Publications View
Multiple guidance mechanisms control axon growth to generate precise T-shaped bifurcation during dorsal funiculus development in the spinal cord.
Authors: Authors: Curran BM, Nickerson KR, Yung AR, Goodrich LV, Jaworski A, Tessier-Lavigne M, Ma L.
Elife
View full abstract on Pubmed
A Pilot Randomized Controlled Trial of the Family Assessment and Feedback Intervention (FAFI): Effects on Mental Health Literacy and Attitudinal Engagement with Health Supports and Services.
Authors: Authors: Ivanova MY, Hall A, Weinberger S, Buckingham SL, Copeland WE, Crockett P, Dainer-Best J, D'Alberto C, Dewey L, Foret D, Galano M, Goodrich L, Holly L, Lane NE, Leahy M, Lerner M, Marsh J, McGinnis EW, Paiva-Salisbury M, Shaw JS, Swift P, Tinker R, Hudziak JJ.
Child Psychiatry Hum Dev
View full abstract on Pubmed
Satellite Glial Cells: No Longer the Most Overlooked Glia.
Authors: Authors: Birren SJ, Goodrich LV, Segal RA.
Cold Spring Harb Perspect Biol
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The auditory midbrain mediates tactile vibration sensing.
Authors: Authors: Huey EL, Turecek J, Delisle MM, Mazor O, Romero GE, Dua M, Sarafis ZK, Hobble A, Booth KT, Goodrich LV, Corey DP, Ginty DD.
bioRxiv
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An Anatomical and Physiological Basis for Coincidence Detection Across Time Scales in the Auditory System.
Authors: Authors: Kreeger LJ, Honnuraiah S, Maeker S, Shea S, Fishell G, Goodrich LV.
bioRxiv
View full abstract on Pubmed
A transcriptomic taxonomy of mouse brain-wide spinal projecting neurons.
Authors: Authors: Winter CC, Jacobi A, Su J, Chung L, van Velthoven CTJ, Yao Z, Lee C, Zhang Z, Yu S, Gao K, Duque Salazar G, Kegeles E, Zhang Y, Tomihiro MC, Zhang Y, Yang Z, Zhu J, Tang J, Song X, Donahue RJ, Wang Q, McMillen D, Kunst M, Wang N, Smith KA, Romero GE, Frank MM, Krol A, Kawaguchi R, Geschwind DH, Feng G, Goodrich LV, Liu Y, Tasic B, Zeng H, He Z.
Nature
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Control of T-shaped Bifurcation by Multiple Guidance Mechanisms during Dorsal Funiculus Development in the Spinal Cord.
Authors: Authors: Curran BM, Nickerson KR, Yung AR, Goodrich LV, Jaworski A, Tessier-Lavigne M, Ma L.
bioRxiv
View full abstract on Pubmed
High temporal frequency light response in mouse retina is mediated by ON and OFF bipolar cells and requires FAT3 signaling.
Authors: Authors: Avilés EC, Wang SK, Patel S, Shi S, Lin L, Kefalov VJ, Goodrich LV, Cepko CL, Xue Y.
bioRxiv
View full abstract on Pubmed
The Vermont Family Based Approach in Primary Care Pediatrics: Effects on Children's and Parents' Emotional and Behavioral Problems and Parents' Health-Related Quality of Life.
Authors: Authors: Ivanova MY, Hall A, Weinberger S, Buckingham SL, Copeland WE, Crockett P, Dainer-Best J, D'Alberto C, Dewey L, Foret D, Galano M, Goodrich L, Holly L, Lane N, Leahey M, Lerner M, Marsh J, McGinnis E, Paiva-Salisbury M, Shaw JS, Swift P, Tinker R, Hudziak JJ.
Child Psychiatry Hum Dev
View full abstract on Pubmed
Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system.
Authors: Authors: Frank MM, Sitko AA, Suthakar K, Torres Cadenas L, Hunt M, Yuk MC, Weisz C, Goodrich LV.
Elife
View full abstract on Pubmed