Wade Regehr, Ph.D.

Synaptic Plasticity and Cerebellar Function

The lab studies diverse topics ranging from the control of neurotransmitter release to the behavioral roles of the cerebellum.  Synaptic plasticity has been a long-standing interest of the lab. In recent years we have focused on the molecular control of release kinetics and short-term synaptic plasticity, and the functional and behavioral roles of these synaptic properties.  We also study the cerebellum.  It is increasingly apparent that the cerebellar circuit and behavioral roles of the cerebellum are much more complex than previously appreciated.  Our studies clarify circuitry, and provide insights into how the cerebellum controls various behaviors, and how cerebellar disfunction leads to neurological disorders such as autism.