Bernardo Sabatini, M.D., Ph.D.

Title: Alice and Rodman W. Moorhead III Professor of Neurobiology, Harvard Medical School; Co-Director of the Kempner Institute for the Study of Natural and Artificial Intelligence at Harvard University; Investigator, Howard Hughes Medical Institute.

The Aim

The Sabatini Lab explores how brain connections support learning, behavior, and decision making.

The Impact

Learning to walk, to read, or to navigate a new city requires the brain to constantly revise its own wiring in response to experience. The Sabatini Lab uses advanced technologies to examine the cellular and molecular mechanisms that make this plasticity possible. Clarifying our understanding of the circuits that connect reward, motivation, and action could help develop new therapies for those living with Tourette's, OCD, and addiction.

A Closer Look

Article: Harvard Medicine Magazine, Fall 2018 – A Harvard Medicine feature on HMS researchers building advanced imaging tools—like custom microscopes and tissue-clearing methods—to reveal hidden details of cells, brains, and tumors.

Article: The Johns Hopkins News-Letter, October 2019 – A Johns Hopkins News-Letter article reporting on Dr. Bernardo Sabatini’s talk about how abnormal development and signaling in basal ganglia circuits, studied using genetically modified mice, may underlie repetitive behaviors in autism and other movement disorders.

Contact

Email: bernardo_sabatini@hms.harvard.edu
Lab website: sabatini.hms.harvard.edu