Rosalind Segal

Rosalind Segal, M.D., Ph.D.

Professor of Neurobiology, Dana-Farber Cancer Institute
Dean for Graduate Education, Harvard Medical School
617-632-4737
Segal Lab Website

Intercellular Communication

Our research focuses on intercellular communication: how growth factor signaling pathways regulate brain development, and how these pathways contribute to abnormal proliferation, migration and survival in brain tumors and in other neurologic disorders.

Publications View
SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells.
Authors: Authors: Klein RS, Rubin JB, Gibson HD, DeHaan EN, Alvarez-Hernandez X, Segal RA, Luster AD.
Development
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Neurotrophins: which way did they go?
Authors: Authors: Segal R.
Sci STKE
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Generation and utilization of phosphorylation state-specific antibodies to investigate signaling pathways.
Authors: Authors: Alberta JA, Segal RA.
Curr Protoc Neurosci
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Rett syndrome model suggests MECP2 gives neurons the quiet they need to think.
Authors: Authors: Carter AR, Segal RA.
Nat Neurosci
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Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression.
Authors: Authors: Choi DY, Toledo-Aral JJ, Segal R, Halegoua S.
Mol Cell Biol
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Surveillance programs for early stage non-seminomatous testicular cancer: a practice guideline.
Authors: Authors: Segal R, Lukka H, Klotz LH, Eady A, Bestic N, Johnston M.
Can J Urol
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Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial.
Authors: Authors: Segal R, Evans W, Johnson D, Smith J, Colletta S, Gayton J, Woodard S, Wells G, Reid R.
J Clin Oncol
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Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFalpha monoclonal antibody and by pentoxiphylline.
Authors: Authors: Segal R, Dayan M, Zinger H, Mozes E.
Lupus
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Sustained signaling by PLCgamma mediates NGF-triggered gene expression
Authors: Authors: Choi DY, Toledo-Aral JJ, Segal RA, Halegoua S
Mol Cell Bio
Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.
Authors: Authors: O'Brien SP, Seipel K, Medley QG, Bronson R, Segal R, Streuli M.
Proc Natl Acad Sci U S A
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