Rosalind Segal

Rosalind Segal, M.D., Ph.D.

Professor of Neurobiology, Dana-Farber Cancer Institute
Dean for Graduate Education, Harvard Medical School
617-632-4737
Segal Lab Website

Intercellular Communication

Our research focuses on intercellular communication: how growth factor signaling pathways regulate brain development, and how these pathways contribute to abnormal proliferation, migration and survival in brain tumors and in other neurologic disorders.

Publications View
Rett syndrome model suggests MECP2 gives neurons the quiet they need to think.
Authors: Authors: Carter AR, Segal RA.
Nat Neurosci
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Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression.
Authors: Authors: Choi DY, Toledo-Aral JJ, Segal R, Halegoua S.
Mol Cell Biol
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Surveillance programs for early stage non-seminomatous testicular cancer: a practice guideline.
Authors: Authors: Segal R, Lukka H, Klotz LH, Eady A, Bestic N, Johnston M.
Can J Urol
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Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial.
Authors: Authors: Segal R, Evans W, Johnson D, Smith J, Colletta S, Gayton J, Woodard S, Wells G, Reid R.
J Clin Oncol
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Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFalpha monoclonal antibody and by pentoxiphylline.
Authors: Authors: Segal R, Dayan M, Zinger H, Mozes E.
Lupus
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Sustained signaling by PLCgamma mediates NGF-triggered gene expression
Authors: Authors: Choi DY, Toledo-Aral JJ, Segal RA, Halegoua S
Mol Cell Bio
Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.
Authors: Authors: O'Brien SP, Seipel K, Medley QG, Bronson R, Segal R, Streuli M.
Proc Natl Acad Sci U S A
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Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation.
Authors: Authors: Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA.
J Neurosci
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Immune response of SLE patients to peptides based on the complementarity determining regions of a pathogenic anti-DNA monoclonal antibody.
Authors: Authors: Dayan M, Segal R, Sthoeger Z, Waisman A, Brosh N, Elkayam O, Eilat E, Fridkin M, Mozes E.
J Clin Immunol
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Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice.
Authors: Authors: Borghesani PR, Alt FW, Bottaro A, Davidson L, Aksoy S, Rathbun GA, Roberts TM, Swat W, Segal RA, Gu Y.
Proc Natl Acad Sci U S A
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