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Publications

Defining brain wiring patterns and mechanisms through gene trapping in mice.

Mouse patched1 controls body size determination and limb patterning.

Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube.

Recruitment of a hedgehog regulatory circuit in butterfly eyespot evolution.

Hedgehog and patched in neural development and disease.

Altered neural cell fates and medulloblastoma in mouse patched mutants.

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.

Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb.

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog.

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