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David D Ginty, Ph.D.

Edward R. and Anne G. Lefler Professor of Neurobiology, Harvard Medical School
Head of the Department of Neurobiology, Harvard Medical School
Publications View
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure.
Authors: Authors: Merte J, Jensen D, Wright K, Sarsfield S, Wang Y, Schekman R, Ginty DD.
Nat Cell Biol
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Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS.
Authors: Authors: Tran TS, Rubio ME, Clem RL, Johnson D, Case L, Tessier-Lavigne M, Huganir RL, Ginty DD, Kolodkin AL.
Nature
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Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.
Authors: Authors: Kolk SM, Gunput RA, Tran TS, van den Heuvel DM, Prasad AA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JP, Smidt MP, Pasterkamp RJ.
J Neurosci
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LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.
Authors: Authors: Mandai K, Guo T, St Hillaire C, Meabon JS, Kanning KC, Bothwell M, Ginty DD.
Neuron
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Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.
Authors: Authors: Newbern J, Zhong J, Wickramasinghe RS, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O'Loughlin B, Wikenheiser J, Gargesha M, Doughman YQ, Charron J, Ginty DD, Watanabe M, Saitta SC, Snider WD, Landreth GE.
Proc Natl Acad Sci U S A
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The brain-derived neurotrophic factor receptor TrkB is critical for the acquisition but not expression of conditioned incentive value.
Authors: Authors: Johnson AW, Chen X, Crombag HS, Zhang C, Smith DR, Shokat KM, Gallagher M, Holland PC, Ginty DD.
Eur J Neurosci
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Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.
Authors: Authors: Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD.
Neuron
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A model for neuronal competition during development.
Authors: Authors: Deppmann CD, Mihalas S, Sharma N, Lonze BE, Niebur E, Ginty DD.
Science
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Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons.
Authors: Authors: Makita T, Sucov HM, Gariepy CE, Yanagisawa M, Ginty DD.
Nature
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