Rosalind Segal

Rosalind Segal, M.D., Ph.D.

Professor of Neurobiology, Dana-Farber Cancer Institute
Dean for Graduate Education, Harvard Medical School
617-632-4737
Segal Lab Website

Intercellular Communication

Our research focuses on intercellular communication: how growth factor signaling pathways regulate brain development, and how these pathways contribute to abnormal proliferation, migration and survival in brain tumors and in other neurologic disorders.

Publications View
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis.
Authors: Authors: Zhou P, Alfaro J, Chang EH, Zhao X, Porcionatto M, Segal RA.
Dev Cell
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Neuromuscular junction defects in mice with mutation of dynein heavy chain 1.
Authors: Authors: Courchesne SL, Pazyra-Murphy MF, Lee DJ, Segal RA.
PLoS One
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Sensory neuropathy attributable to loss of Bcl-w.
Authors: Authors: Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA.
J Neurosci
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Equipment to manage a difficult airway during anaesthesia.
Authors: Authors: Baker PA, Flanagan BT, Greenland KB, Morris R, Owen H, Riley RH, Runciman WB, Scott DA, Segal R, Smithies WJ, Merry AF.
Anaesth Intensive Care
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The longer U(T)R, the further you go.
Authors: Authors: Cosker KE, Segal RA.
Nat Neurosci
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Live or let die: CCM2 provides the link.
Authors: Authors: Gruber-Olipitz M, Segal RA.
Neuron
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A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w.
Authors: Authors: Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, Heerssen HM, Watson FL, Kim T, Greenberg ME, Segal RA.
J Neurosci
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Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.
Authors: Authors: Arimura N, Kimura T, Nakamuta S, Taya S, Funahashi Y, Hattori A, Shimada A, Ménager C, Kawabata S, Fujii K, Iwamatsu A, Segal RA, Fukuda M, Kaibuchi K.
Dev Cell
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Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.
Authors: Authors: Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA.
Nat Neurosci
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Olfactory behavioral testing in the adult mouse.
Authors: Authors: Witt RM, Galligan MM, Despinoy JR, Segal R.
J Vis Exp
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