
Jeffrey S. Flier, MD
Higginson Professor of Physiology and Medicine
Harvard University Distinguished Service Professor
Former Dean of the Faculty of Medicine (2007- 2016)
Publications View
Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans.
Authors: Authors: Mantzoros CS, Ozata M, Negrao AB, Suchard MA, Ziotopoulou M, Caglayan S, Elashoff RM, Cogswell RJ, Negro P, Liberty V, Wong ML, Veldhuis J, Ozdemir IC, Gold PW, Flier JS, Licinio J.
J Clin Endocrinol Metab
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J Clin Endocrinol Metab
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Cell biology. Chewing the fat--ACC and energy balance.
Obesity and the regulation of energy balance.
Divergent roles of SHP-2 in ERK activation by leptin receptors.
Authors: Authors: Bjørbaek C, Buchholz RM, Davis SM, Bates SH, Pierroz DD, Gu H, Neel BG, Myers MG, Flier JS.
J Biol Chem
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J Biol Chem
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Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance.
Authors: Authors: Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E.
J Clin Invest
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J Clin Invest
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Diabetes. The missing link with obesity?
Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling.
Authors: Authors: Harris M, Aschkenasi C, Elias CF, Chandrankunnel A, Nillni EA, Bjøorbaek C, Elmquist JK, Flier JS, Hollenberg AN.
J Clin Invest
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J Clin Invest
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SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985.
Authors: Authors: Bjorbak C, Lavery HJ, Bates SH, Olson RK, Davis SM, Flier JS, Myers MG.
J Biol Chem
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J Biol Chem
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Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways.
Authors: Authors: Nillni EA, Vaslet C, Harris M, Hollenberg A, Bjørbak C, Flier JS.
J Biol Chem
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J Biol Chem
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Editorial: leptin as a therapeutic agent--trials and tribulations.