Flier

Jeffrey S. Flier, MD

Higginson Professor of Physiology and Medicine
Harvard University Distinguished Service Professor
Former Dean of the Faculty of Medicine (2007- 2016)
Publications View
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts.
Authors: Authors: Koulmanda M, Budo E, Bonner-Weir S, Qipo A, Putheti P, Degauque N, Shi H, Fan Z, Flier JS, Auchincloss H, Zheng XX, Strom TB.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states.
Authors: Authors: Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E.
Cell Metab
View full abstract on Pubmed
The adipocyte as an active participant in energy balance and metabolism.
Authors: Authors: Badman MK, Flier JS.
Gastroenterology
View full abstract on Pubmed
Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity.
Authors: Authors: Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM.
Cell Metab
View full abstract on Pubmed
Attenuation of leptin and insulin signaling by SOCS proteins.
Authors: Authors: Howard JK, Flier JS.
Trends Endocrinol Metab
View full abstract on Pubmed
TLR4 links innate immunity and fatty acid-induced insulin resistance.
Authors: Authors: Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS.
J Clin Invest
View full abstract on Pubmed
Leptin regulation of the mesoaccumbens dopamine pathway.
Authors: Authors: Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS.
Neuron
View full abstract on Pubmed
Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.
Authors: Authors: Kievit P, Howard JK, Badman MK, Balthasar N, Coppari R, Mori H, Lee CE, Elmquist JK, Yoshimura A, Flier JS.
Cell Metab
View full abstract on Pubmed
Neuroscience. Regulating energy balance: the substrate strikes back.
Authors: Authors: Flier JS.
Science
View full abstract on Pubmed
The antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes.
Authors: Authors: Drukarch B, Flier J, Jongenelen CA, Andringa G, Schoffelmeer AN.
J Neural Transm (Vienna)
View full abstract on Pubmed