Jeffrey S. Flier

Jeffrey S. Flier, MD

Higginson Professor of Physiology and Medicine

Harvard University Distinguished Service Professor

Former Dean of the Faculty of Medicine (2007- 2016)

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Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice.

Authors: Authors: Czupryn A, Zhou YD, Chen X, McNay D, Anderson MP, Flier JS, Macklis JD.
Science 2011-11-25
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Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo.

Authors: Authors: Fisher FM, Estall JL, Adams AC, Antonellis PJ, Bina HA, Flier JS, Kharitonenkov A, Spiegelman BM, Maratos-Flier E.
Endocrinology 2011-08-01
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Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism.

Authors: Authors: Aboulaich N, Chui PC, Asara JM, Flier JS, Maratos-Flier E.
Diabetes 2011-03-01
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Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance.

Authors: Authors: Briancon N, McNay DE, Maratos-Flier E, Flier JS.
Diabetes 2010-12-01
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Obesity is a fibroblast growth factor 21 (FGF21)-resistant state.

Authors: Authors: Fisher FM, Chui PC, Antonellis PJ, Bina HA, Kharitonenkov A, Flier JS, Maratos-Flier E.
Diabetes 2010-11-01
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Lasker lauds leptin.

Authors: Authors: Flier JS, Maratos-Flier E.
Cell Metab 2010-10-06
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Lasker lauds leptin.

Authors: Authors: Flier JS, Maratos-Flier E.
Cell 2010-10-01
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Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.

Authors: Authors: Adams AC, Astapova I, Fisher FM, Badman MK, Kurgansky KE, Flier JS, Hollenberg AN, Maratos-Flier E.
J Biol Chem 2010-05-07
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Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicine.

Authors: Authors: Nesse RM, Bergstrom CT, Ellison PT, Flier JS, Gluckman P, Govindaraju DR, Niethammer D, Omenn GS, Perlman RL, Schwartz MD, Thomas MG, Stearns SC, Valle D.
Proc Natl Acad Sci U S A 2010-01-26
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Gut check: testing a role for the intestinal microbiome in human obesity.

Authors: Authors: Flier JS, Mekalanos JJ.
Sci Transl Med 2009-11-11
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