Flier

Jeffrey S. Flier, MD

Higginson Professor of Physiology and Medicine
Harvard University Distinguished Service Professor
Former Dean of the Faculty of Medicine (2007- 2016)
Publications View
IP-10 mRNA expression in cultured keratinocytes is suppressed by inhibition of protein kinase-C and tyrosine kinase and elevation of cAMP.
Authors: Authors: Boorsma DM, Flier J, van den Brink EN, Sampat S, Walg HL, Willemze R, Tensen CP, Stoof TJ.
Cytokine
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Regulation of neuronal and glial proteins by leptin: implications for brain development.
Authors: Authors: Ahima RS, Bjorbaek C, Osei S, Flier JS.
Endocrinology
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Big deal about a little insulin.
Authors: Authors: Flier JS.
Nat Med
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Activation of SOCS-3 Messenger Ribonucleic Acid in the Hypothalamus by Ciliary Neurotrophic Factor.
Authors: Authors: Bjørbæk C, Elmquist JK, El-Haschimi K, Kelly J, Ahima RS, Hileman S, Flier JS.
Endocrinology
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Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).
Authors: Authors: Tensen CP, Flier J, Van Der Raaij-Helmer EM, Sampat-Sardjoepersad S, Van Der Schors RC, Leurs R, Scheper RJ, Boorsma DM, Willemze R.
J Invest Dermatol
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Activation of SOCS-3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor.
Authors: Authors: Bjørbaek C, Elmquist JK, El-Haschimi K, Kelly J, Ahima RS, Hileman S, Flier JS.
Endocrinology
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Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation.
Authors: Authors: Uotani S, Bjørbaek C, Tornøe J, Flier JS.
Diabetes
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Mice lacking melanin-concentrating hormone are hypophagic and lean.
Authors: Authors: Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E.
Nature
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Sex differences in circulating human leptin pulse amplitude: clinical implications.
Authors: Authors: Licinio J, Negrão AB, Mantzoros C, Kaklamani V, Wong ML, Bongiorno PB, Negro PP, Mulla A, Veldhuis JD, Cearnal L, Flier JS, Gold PW.
J Clin Endocrinol Metab
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Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice.
Authors: Authors: Tritos NA, Elmquist JK, Mastaitis JW, Flier JS, Maratos-Flier E.
Endocrinology
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